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Filtered Search Results
Cayman Chemical A83016F 2.5mg
A DNA alkylating agent active metabolite of dacarbazine (DTIC) active degradation product of temozolomide cytotoxic to L-cells and decreases thymidine and uridine uptake by 55 and 65 respectively at 1 mM cytotoxic to TLX5 murine lymphoma cells induces formation of mammary adenofibromas in rats when administered at a cumulative dose of 890 mg per animal over 14 weeks
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Cayman Chemical CaveolIn13 Blockng PepID 200ug
An inhibitor of menin-MLL fusion protein interactions (IC50 446 nM) binds to menin (Kd 158 nM) and inhibits the menin-MLL-AF9 interaction in HEK293 cells inhibits growth of mouse BMCs expressing the Hoxa9 transformation-dependent MLL-AF9 (GI50 5 UM) inhibits the growth of MV4 KOPN-8 ML-2 and MonoMac6 MLL cells expressing MLL fusion proteins (GI50s 9 5 7 2 8 7 and 18 M respectively)
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